HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3H-2-benzofuran-1-one → 5-[5-Fluoro-4-(1-hydroxy-ethyl)-pyridin-3-yl]-3H-Isobenzofuran-1-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3H-2-benzofuran-1-one | HCID 58074623 | — |
| Reactant | 1-(3-Bromo-5-Fluoro-pyridin-4-yl)-ethanol | HCID 69937909 | — |
| Product | 5-[5-Fluoro-4-(1-hydroxy-ethyl)-pyridin-3-yl]-3H-Isobenzofuran-1-one | HCID 69937515 | — |
Reaction Steps
5-(4,4,5,5-Tetramethyl-[1,3,2]dioxaborolan-2-yl)-3H-isobenzofuran-1-one and 1-(3-bromo-5-fluoro-pyridin-4-yl)-ethanol were reacted according to the procedure described in Example 35.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08519134B2 |
| Source dataset | uspto-grants-2013_08 |
| ORD ID | ord-6645e1fb2f2f4b3b9995485a645bd34b |
| Source note | uspto-grants-2013_08 |