HuagongsheHuagongshe Chemistry Print Report · For research reference only
Cis-3-azido-6-benzhydryl-tetrahydropyran → Cis-(6-benzhydryl-tetrahydropyran-3-yl)-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Cis-3-azido-6-benzhydryl-tetrahydropyran | HCID 11630718 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | Cis-(6-benzhydryl-tetrahydropyran-3-yl)-amine | HCID 11565229 | 78% |
Reaction Steps
Cis-5-azido-2-diphenylmethyl-tetrahydropyran 14 (0.3 g, 1.02 mmol) in methanol (25 ml) was hydrogenated under the catalyst of 10% Pd—C (0.03 g, 10% wt) for 4 hr (Procedure C) to give cis-5-amino-2-diphenylmethyl-tetrahydropyran 15 (0.21 g, 78%) as an oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08519159B2 |
| Source dataset | uspto-grants-2013_08 |
| ORD ID | ord-142991e3e91b45c4937b35005d171ef4 |
| Source note | uspto-grants-2013_08 |