HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methanol → HCID 11245759, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methanol | HCID 887 | — |
| Reactant | Benzylamine | HCID 7504 | — |
| Reactant | (1R,4R,6S)-4-benzhydryl-3,7-dioxa-bicyclo[4.1.0]-heptane | HCID 86605347 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 11245759 | HCID 11245759 | — |
Reaction Steps
(1R,4R,6S)-4-benzhydryl-3,7-dioxa-bicyclo[4.1.0]-heptane 28c (0.022 g, 0.082 mmol) was reacted with benzylamine (0.18 g, 1.64 mmol) in ethanol (Procedure E) to yield (2R,4S,5S)-2-benzhydryl-5-benzylamino-tetrahydro-pyran-4-ol, (+)-29d 0.025 g (81%, [α]D=(+)53.7, c=1, MeOH).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08519159B2 |
| Source dataset | uspto-grants-2013_08 |
| ORD ID | ord-f29a3e39efc744c5a4de2b5806781d20 |
| Source note | uspto-grants-2013_08 |