HCID 66890986, compound → HCID 66889473, compound

Participants

Reaction Steps

21.2 mg of tert-butyl 4-((4-methyl-6-((1-((2-(trimethylsilyl)ethoxy)methyl)-1H-pyrazol-3-yl)amino)pyrimidin-2-yl)methyl)piperidine-1-carboxylate was dissolved in 1 ml of formic acid at room temperature, followed by stirring the reaction mixture at room temperature for 1 hour. The reaction mixture was concentrated in vacuo, basified with saturated aqueous sodium bicarbonate solution, and extracted with chloroform. The organic layer was washed with brine, dried over anhydrous magnesium sulfate, and filtered. The filtrate was concentrated in vacuo to give the title compound.

Provenance & Evidence