Hydrochloric Acid → HCID 58097129, compound

Participants

Reaction Steps

To 1.21 g of 1-tert-butyl 4-ethyl 4-((6-((1-tert-butyl-1H-pyrazol-5-yl)amino)pyridin-2-yl)methyl)piperidine-1,4-dicarboxylate were added 12 ml of 4 M hydrogen chloride in 1,4-dioxane and 3 ml of ethanol at room temperature. The reaction mixture was stirred at room temperature for 30 minutes, and concentrated in vacuo. The resulting residue was basified with saturated aqueous sodium bicarbonate solution, and extracted with ethyl acetate. The resulting ethyl acetate solution was dried over anhydrous magnesium sulfate, and filtered. The filtrate was concentrated in vacuo to give the title compound as a pale brown oil.

Provenance & Evidence