Sodium Hydroxide → HCID 57942137, compound

HRID 1898012Notes

Reaction equation

HRID 1898012 reaction equation
C[O:2][C:3]([C:5]1[C:10]([NH:11][S:12]([C:15]2[CH:20]=[CH:19][C:18]([Cl:21])=[C:17]([Cl:22])[CH:16]=2)(=[O:14])=[O:13])=[N:9][CH:8]=[CH:7][N:6]=1)=[O:4].[OH-].[Na+]>CO>[Cl:22][C:17]1[CH:16]=[C:15]([S:12]([NH:11][C:10]2[C:5]([C:3]([OH:4])=[O:2])=[N:6][CH:7]=[CH:8][N:9]=2)(=[O:14])=[O:13])[CH:20]=[CH:19][C:18]=1[Cl:21]

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 57942319HCID 57942319, compound

Product 1

HCID 57942137HCID 57942137, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

This title compound was prepared following procedure described in example 42 step 2 wherein 3-(3,4-dichloro-benzenesulfonylamino)-pyrazine-2-carboxylic acid methyl ester was treated with 2M NaOH and methanol. Usual work up afforded the above title product as a white powder. MS: (M+Na)/z=382.0.

Workup

  1. customThis title compound was prepared following procedure

Sources & evidence

ORD record
ord-bae8877b8ca743b188acab52dfa1a70a
Source dataset
uspto-grants-2013_08
Patent number
US08519135B2

Reaction notes

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