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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1898218Generated: October 27, 2026

2-Fluoro-5-formylpyridine → 4-tert-Butyl-N-[5-chloro-2-(6-fluoro-pyridine-3-carbonyl)-pyridin-3-yl]-N-methoxymethyl-benzenesulfonamide

https://huagongshe.com/reaction/1898218

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Fluoro-5-formylpyridineHCID 16414246—
ReactantN-(2-bromo-5-chloro-pyridin-3-yl)-4-tert-butyl-N-methoxymethyl-benzenesulfonamideHCID 57942088—
Product4-tert-Butyl-N-[5-chloro-2-(6-fluoro-pyridine-3-carbonyl)-pyridin-3-yl]-N-methoxymethyl-benzenesulfonamideHCID 5794256338%

Reaction Steps

4-tert-Butyl-N-[5-chloro-2-(6-fluoro-pyridine-3-carbonyl)-pyridin-3-yl]-N-methoxymethyl-benzenesulfonamide was prepared from N-(2-bromo-5-chloro-pyridin-3-yl)-4-tert-butyl-N-methoxymethyl-benzenesulfonamide and 6-fluoro-pyridine-3-carbaldehyde using the procedure described in examples 35 and 36.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08519135B2
Source datasetuspto-grants-2013_08
ORD IDord-910132688d004294b63846faa43d9aad
Source noteuspto-grants-2013_08