Hydrogen Peroxide → HCID 178507593, compound

Participants

Reaction Steps

To a solution of 5-chloropyridin-2-amine (0.500 g, 3.90 mmol) in acetic acid (2.0 mL) was added 50% hydrogen peroxide (2.0 mL). The reaction mass was refluxed for 24 h. The excess of solvent was removed under vacuum to afford 0.450 g of the desired product. 1HNMR (DMSO-d6): δ 6.79 (d, J=8.7 Hz, 1H), 6.93 (s, 2H), 7.21 (d, J=8.7 Hz, 1H), 8.25 (s, 1H); MS [M+H]+: 145.23.

Provenance & Evidence