HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Methoxide → Methyl 2-methoxy-4-(methylamino)-5-nitrobenzoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Methoxide | HCID 10942334 | — |
| Reactant | HCID 59395139 | HCID 59395139 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | Methyl 2-methoxy-4-(methylamino)-5-nitrobenzoate | HCID 67331452 | 29,629.699% |
Reaction Steps
The title compound was prepared following the procedure described for Step-4 of Intermediate-1 using methyl 2-fluoro-4-(methylamino)-5-nitrobenzoate (12.00 g, 0.0562 mmol) and sodium methoxide (22.73 g, 0.4210 mmol), methanol to afford 4.00 g of the desired product. 1HNMR (DMSO-d6): δ 3.02 (d, J=4.5 Hz, 3H), 3.75 (s, 3H), 3.94 (s, 3H), 6.28 (s, 1H), 8.57 (s, 1H), 8.62 (bs, 1H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08519149B2 |
| Source dataset | uspto-grants-2013_08 |
| ORD ID | ord-236b0743bec048bfb75bfd2cec987557 |
| Source note | uspto-grants-2013_08 |