3-Chloro-2-methyl-1-propene → HCID 67502740, compound

Participants

Reaction Steps

The title compound was prepared following the procedure described for Step-6 of Intermediate-1 using methyl 2-hydroxy-4-(methylamino)-5-nitrobenzoate (4.00 g, 0.0176 mmol), methallyl chloride (2.8 g, 0.0318 mmol), potassium carbonate (4.38 g, 0.037 mmol) and DMF (50.0 mL) to afford 3.500 g of desired product. 1HNMR (DMSO-d6): δ 1.81 (s, 3H), 3.00 (d, J=4.8 Hz, 3H), 3.76 (s, 3H), 4.65 (s, 2H), 5.00 (s, 1H), 5.24 (s, 1H), 6.30 (s, 1H), 8.59 (s, 2H); [M+H]+: 281.00.

Provenance & Evidence