HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Hydrochloric Acid → 4-Cyclopropylaniline
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Hydrochloric Acid | HCID 313 | — |
| Edukt | 1-Cyclopropyl-4-nitrobenzene | HCID 312713 | — |
| Katalysator | Iron | HCID 23925 | — |
| Lösungsmittel | Methanol | HCID 887 | — |
| Produkt | 4-Cyclopropylaniline | HCID 12253927 | 553,4% |
Reaktionsschritte
The title compound was prepared following the procedure described for Step-9 of Intermediate-1 using 1-cyclopropyl-4-nitrobenzene (0.400 g, 0.407 mmol), methanol (10 mL), iron powder (catalytic amount) and conc. HCl (0.5 mL) to afford 0.300 g of the desired product. 1HNMR (DMSO-d6): δ 0.43-0.48 (m, 2H), 0.74-0.80 (m, 2H), 1.23-1.74 (m, 1H), 4.79 (s, 2H), 6.44 (d, J=8.1 Hz, 2H), 6.73 (d, J=8.1 Hz, 2H); [M+H]+: 134.20.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08519149B2 |
| Quelldatensatz | uspto-grants-2013_08 |
| ORD ID | ord-6200688894fa480bbbfd8f766e277357 |
| Quellennotiz | uspto-grants-2013_08 |