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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 1898333Erstellt: 25. Oktober 2026

Hydrochloric Acid → 4-Cyclopropylaniline

https://huagongshe.com/reaction/1898333

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
EduktHydrochloric AcidHCID 313—
Edukt1-Cyclopropyl-4-nitrobenzeneHCID 312713—
KatalysatorIronHCID 23925—
LösungsmittelMethanolHCID 887—
Produkt4-CyclopropylanilineHCID 12253927553,4%

Reaktionsschritte

The title compound was prepared following the procedure described for Step-9 of Intermediate-1 using 1-cyclopropyl-4-nitrobenzene (0.400 g, 0.407 mmol), methanol (10 mL), iron powder (catalytic amount) and conc. HCl (0.5 mL) to afford 0.300 g of the desired product. 1HNMR (DMSO-d6): δ 0.43-0.48 (m, 2H), 0.74-0.80 (m, 2H), 1.23-1.74 (m, 1H), 4.79 (s, 2H), 6.44 (d, J=8.1 Hz, 2H), 6.73 (d, J=8.1 Hz, 2H); [M+H]+: 134.20.

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS08519149B2
Quelldatensatzuspto-grants-2013_08
ORD IDord-6200688894fa480bbbfd8f766e277357
Quellennotizuspto-grants-2013_08