Sulfuric Acid → HCID 178496999, compound

Participants

Reaction Steps

The title compound was prepared following the procedure described for step-3 of intermediate-55 using methyl 2-[(2-chloro-6-fluorophenyl)amino]-6-hydroxy-1H-benzimidazole-5-carboxylate (0.380 g, 1.134 mmol), conc. H2SO4 (1.2 mL) and KNO3 (0.109 g, 1.077 mmol) to afford 0.320 g of the desired product. 1HNMR (DMSO-d6): δ 3.92 (s, 3H), 7.40-7.47 (m, 3H), 7.72 (s, 1H), 9.98 (m, 1H), 11.00-12.00 (s, 2H); MS [M+H]+: 381.03.

Provenance & Evidence