Phosphoric Acid → HCID 178422763, compound

Participants

Reaction Steps

The title compound was prepared following the procedure described for Example-169 using 2-[(2-chloro-6-fluorophenyl)amino]-7,7-dimethyl-N-[4-(trifluoromethyl)phenyl]-7,8-dihydro-1H-furo[3,2-e]benzimidazole-5-carboxamide (Example-107, 0.100 g), acetone and phosphoric acid to afford 0.040 g of the desired product. 1HNMR (DMSO-d6): δ 1.57 (s, 6H), 3.10 (s, 2H), 7.30-7.33 (m, 2H), 7.41 (d, J=7.5 Hz, 1H), 7.47 (s, 1H), 7.70 (d, J=8.1 Hz, 2H), 7.91 (d, J=8.7 Hz, 2H), 7.99 (s, 1H), 13.0 (br, 5H).

Provenance & Evidence