Sulfuric Acid → HCID 178422764, compound

Participants

Reaction Steps

The title compound was prepared following the procedure described for Example-169 using 2-[(2-chloro-6-fluorophenyl)amino]-7,7-dimethyl-N-[4-(trifluoromethyl)phenyl]-7,8-dihydro-1H-furo[3,2-e]benzimidazole-5-carboxamide (Example-107, 0.100 g), acetone and sulphuric acid to afford 0.040 g of the desired product. 1HNMR (DMSO-d6): δ 1.57 (s, 6H), 2.08 (s, 2H), 3.20 (s, 2H), 7.51-7.55 (m, 3H), 7.58 (s, 1H), 7.73 (d, J=8.7 Hz, 2H), 7.93 (d, J=8.7 Hz, 2H), 10.03 (s, 1H), 13.0-14.0 (br, 2H).

Provenance & Evidence