HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 178422781, compound → HCID 178422782, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 178422781 | HCID 178422781 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | Hydrochloric Acid | HCID 313 | — |
| Product | HCID 178422782 | HCID 178422782 | 182.6% |
Reaction Steps
The title compound was prepared following the procedure described for Example-146 by using 2-[(2-chloro-6-fluorophenyl)amino]-N-[4-fluoro-3-(trifluoromethyl)phenyl]-7,7-dimethyl-7,8-dihydro-1H-furo[3,2-e]benzimidazole-5-carboxamide (Example-104, 0.100 g), THF, conc.HCl to afford 0.065 g of the desired product. 1HNMR (DMSO-d6): δ 1.58 (s, 6H), 3.19 (s, 2H), 7.50-7.63 (m, 4H), 7.88 (m, 2H), 8.30 (d, J=4.2 Hz, 1H), 9.98 (s, 1H), 11.50 (br s, 1H), 12.70 (br s, 2H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08519149B2 |
| Source dataset | uspto-grants-2013_08 |
| ORD ID | ord-3bbc1aed923a4ca289aad03a86abe933 |
| Source note | uspto-grants-2013_08 |