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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1898475Generated: October 31, 2026

HCID 178422767, compound → HCID 178422768, compound

https://huagongshe.com/reaction/1898475

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 178422767HCID 178422767—
SolventTetrahydrofuranHCID 8028—
ProductHydrochloric AcidHCID 313—
ProductHCID 178422768HCID 178422768126.4%

Reaction Steps

The title compound was prepared following the procedure described for Example-146 by using 2-[(2,6-Dichlorophenyl)amino]-7,7-dimethyl-N-[5-(trifluoromethyl)pyridin-2-yl]-7,8-dihydro-1H-furo[3,2-e]benzimidazole-5-carboxamide (Example-101, 0.100 g), THF, conc.HCl to afford 0.045 g of the desired product. 1HNMR (DMSO-d6): δ 1.60 (s, 6H), 3.25 (s, 2H), 7.58 (m, 1H), 7.75 (m, 3H), 8.28 (d, 1H), 8.46 (d, J=8.7 Hz, 1H), 8.78 (s, 1H), 10.42 (s, 1H), 12.00 (s, 1H), 13.20 (s, 2H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08519149B2
Source datasetuspto-grants-2013_08
ORD IDord-7277afe62eeb47b09c5dfae192546669
Source noteuspto-grants-2013_08