HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 178422767, compound → HCID 178422768, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 178422767 | HCID 178422767 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | Hydrochloric Acid | HCID 313 | — |
| Product | HCID 178422768 | HCID 178422768 | 126.4% |
Reaction Steps
The title compound was prepared following the procedure described for Example-146 by using 2-[(2,6-Dichlorophenyl)amino]-7,7-dimethyl-N-[5-(trifluoromethyl)pyridin-2-yl]-7,8-dihydro-1H-furo[3,2-e]benzimidazole-5-carboxamide (Example-101, 0.100 g), THF, conc.HCl to afford 0.045 g of the desired product. 1HNMR (DMSO-d6): δ 1.60 (s, 6H), 3.25 (s, 2H), 7.58 (m, 1H), 7.75 (m, 3H), 8.28 (d, 1H), 8.46 (d, J=8.7 Hz, 1H), 8.78 (s, 1H), 10.42 (s, 1H), 12.00 (s, 1H), 13.20 (s, 2H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08519149B2 |
| Source dataset | uspto-grants-2013_08 |
| ORD ID | ord-7277afe62eeb47b09c5dfae192546669 |
| Source note | uspto-grants-2013_08 |