Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1898503Generated: October 25, 2026

Pyrrolidine → HCID 86657870, compound

https://huagongshe.com/reaction/1898503

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPyrrolidineHCID 31268—
Reactant3-Methylpyrrolidine-3-carbonitrile hydrochlorideHCID 57516601—
Reactant2-cyclopropyl-5-((2-(trimethylsilyl)ethoxy)methyl)-5H-pyrrolo[2,3-b]pyrazine-7-carboxylic acidHCID 57829653—
Reactant2-(1-ethyl-1H-pyrazol-4-yl)-5-((2-(trimethylsilyl)ethoxy)methyl)-5H-pyrrolo[3,2-b]pyrazine-7-carboxylic acidHCID 58438544—
ProductHCID 86657870HCID 86657870—

Reaction Steps

Prepared according to the procedure outlined in Example 1 substituting 3-methylpyrrolidine-3-carbonitrile hydrochloride for pyrrolidine and 2-(1-ethyl-1H-pyrazol-4-yl)-5-((2-(trimethylsilyl)ethoxy)methyl)-5H-pyrrolo[3,2-b]pyrazine-7-carboxylic acid for 2-cyclopropyl-5-(2-trimethylsilanyl-ethoxymethyl)-5H-pyrrolo[2,3-b]pyrazine-7-carboxylic acid. MS: (M+H)+=463; mp=228.0-230.0.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08518945B2
Source datasetuspto-grants-2013_08
ORD IDord-2be879c5348247028b4216d1e438d43f
Source noteuspto-grants-2013_08