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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1898520Generated: October 26, 2026

2,5-Dimethoxyphenylboronic acid → HCID 53386307, compound

https://huagongshe.com/reaction/1898520

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,5-Dimethoxyphenylboronic acidHCID 2734342—
Reactant1-Ethyl-1H-pyrazole-4-boronic acid, pinacol esterHCID 11379045—
Reactant(R)-2-amino-3,3-dimethyl-1-(pyrrolidin-1-yl)butan-1-one hydrochlorideHCID 57516598—
Reactant1-((R)-2-amino-3,3-dimethyl-butyryl)-piperidine-4-carbonitrile trifluoroacetateHCID 67386048—
ProductHCID 53386307HCID 53386307—

Reaction Steps

Prepared according to the procedure outlined in Example 2 substituting 1-((R)-2-amino-3,3-dimethyl-butyryl)-piperidine-4-carbonitrile trifluoroacetate for (R)-2-amino-3,3-dimethyl-1-pyrrolidin-1-yl-butan-1-one hydrochloride in Step 1 and 2,5-dimethoxyphenylboronic acid for 1-ethyl-1H-pyrazole-4-boronic acid pinacol ester in Step 2. MS: (M+H)+=505.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08518945B2
Source datasetuspto-grants-2013_08
ORD IDord-cbf72400abc7466f83e2930e3c492d86
Source noteuspto-grants-2013_08