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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1898528Generated: October 25, 2026

(2R)-2-{[(tert-butoxy)carbonyl]amino}-3,3-dimethylbutanoic acid → HCID 53385991, compound

https://huagongshe.com/reaction/1898528

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(2R)-2-{[(tert-butoxy)carbonyl]amino}-3,3-dimethylbutanoic acidHCID 7005057—
Reactant2-(1-ethyl-1H-pyrazol-4-yl)-5-((2-(trimethylsilyl)ethoxy)methyl)-5H-pyrrolo[3,2-b]pyrazine-7-carboxylic acidHCID 58438544—
ReactantHCID 58438583HCID 58438583—
ProductHCID 53385991HCID 53385991—

Reaction Steps

Prepared according to the procedure outlined in Example 1 substituting (R)-tert-butoxycarbonylamino-(1-methyl-cyclopropyl)-acetic acid for Boc-D-tert-leucine and 2-(1-ethyl-1H-pyrazol-4-yl)-5-((2-(trimethylsilyl)ethoxy)methyl)-5H-pyrrolo[3,2-b]pyrazine-7-carboxylic acid for 2-cyclopropyl-5-(2-trimethylsilanyl-ethoxymethyl)-5H-pyrrolo[2, 3-1)]pyrazine-7-carboxylic acid. MS: (M+H)+=422.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08518945B2
Source datasetuspto-grants-2013_08
ORD IDord-2fd77aa251db49c8b091f5da9e0844c0
Source noteuspto-grants-2013_08