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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1898571Generated: October 30, 2026

4-(Trifluoromethyl)phenylboronic acid → HCID 58438613, compound

https://huagongshe.com/reaction/1898571

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(Trifluoromethyl)phenylboronic acidHCID 2734389—
Reactant1-Ethyl-1H-pyrazole-4-boronic acid, pinacol esterHCID 11379045—
Reactant(R)-2-amino-3,3-dimethyl-1-(pyrrolidin-1-yl)butan-1-one hydrochlorideHCID 57516598—
Reactant1-((R)-2-amino-3,3-dimethyl-butyryl)-piperidine-4-carbonitrile trifluoroacetateHCID 67386048—
ProductHCID 58438613HCID 58438613—

Reaction Steps

Prepared according to the procedure outlined in Example 2 substituting 1-((R)-2-amino-3,3-dimethyl-butyryl)-piperidine-4-carbonitrile trifluoroacetate for (R)-2-amino-3,3-dimethyl-1-pyrrolidin-1-yl-butan-1-one hydrochloride in Step 1 and 4-(trifluoromethyl)-phenylboronic acid for 1-ethyl-1H-pyrazole-4-boronic acid pinacol ester in Step 2. MS: (M+H)+=513.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08518945B2
Source datasetuspto-grants-2013_08
ORD IDord-5d6e7b12741b4b9ea1cfe8b8cfda16ad
Source noteuspto-grants-2013_08