HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ceric ammonium nitrate → 2-(3-Hydroxy-4-(4-hydroxypiperidin-1-yl)-3-methyl-4-oxobutyl)-3,5,6-trimethylcyclohexa-2,5-diene-1,4-dione
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ceric ammonium nitrate | HCID 180504 | — |
| Reactant | (6-Hydroxy-2,5,7,8-tetramethylchroman-2-yl)(4-hydroxypiperidin-1-yl)methanone | HCID 67263066 | — |
| Product | 2-(3-Hydroxy-4-(4-hydroxypiperidin-1-yl)-3-methyl-4-oxobutyl)-3,5,6-trimethylcyclohexa-2,5-diene-1,4-dione | HCID 42599125 | 90% |
Reaction Steps
Oxidation as described in protocol B, using 100 mg (0.302 mmol) of (6-hydroxy-2,5,7,8-tetramethylchroman-2-yl)(4-hydroxypiperidin-1-yl)methanone and 364 mg CAN (0.664 mmol) yielded 95 mg of a yellow syrup.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08519001B2 |
| Source dataset | uspto-grants-2013_08 |
| ORD ID | ord-b806400cfd42401da5943ec441ea5d7e |
| Source note | uspto-grants-2013_08 |