HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trolox → HCID 10454151, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trolox | HCID 40634 | — |
| Reactant | 1,1'-Carbonyldiimidazole | HCID 68263 | — |
| Reactant | 1-Benzylpiperazine | HCID 75994 | — |
| Product | HCID 10454151 | HCID 10454151 | 68.8% |
Reaction Steps
Following the amide coupling procedure described in protocol A, 506 mg 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid (2.02 mmol), 365 mg CDI (2.25 mmol) and 386 mg 1-benzylpiperazine (2.2 mmol) yielded 568 mg of (4-benzylpiperazin-1-yl)(6-hydroxy-2,5,7,8-tetramethylchroman-2-yl)methanone as a white powder.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08519001B2 |
| Source dataset | uspto-grants-2013_08 |
| ORD ID | ord-cec36a44b2fb4649955b8f018cfc08dd |
| Source note | uspto-grants-2013_08 |