HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ammonia → HCID 53704167, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ammonia | HCID 222 | — |
| Reactant | Methanol | HCID 887 | — |
| Reactant | Trolox | HCID 40634 | — |
| Reactant | 1,1'-Carbonyldiimidazole | HCID 68263 | — |
| Product | HCID 53704167 | HCID 53704167 | 37.7% |
Reaction Steps
Following the amide coupling procedure described in protocol A, 498 mg 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid (1.99 mmol), 367 mg CDI (2.26 mmol) and 1.4 mL of 7.0M NH3 in MeOH (9.8 mmol) produced 187 mg of 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxamide as a white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08519001B2 |
| Source dataset | uspto-grants-2013_08 |
| ORD ID | ord-86af64fc91274066a7b1690ab6ff0b62 |
| Source note | uspto-grants-2013_08 |