反应详情

5.0 g (27.5 mmol) of the chloride from Example 1, Step B and 4.2 g (55.2 mmol) thiourea were heated in 100 ml dry ethanol for 5 h. The solvent was distilled off in vacuo and the residue crystallized from ethanol/water to give the title compound in yellow crystals, m.p. 178°-180° C.

1. distillationThe solvent was distilled off in vacuo
2. customthe residue crystallized from ethanol/water