HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(4-Aminophenyl)benzonitrile → 7-[(2'-Cyanobiphenyl-4-yl)amino]-5-ethylpyrazolo[1,5-a]pyrimidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(4-Aminophenyl)benzonitrile | HCID 1393926 | — |
| Reactant | 7-Chloro-5-ethylpyrazolo[1,5-a]pyrimidine | HCID 10535410 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 7-[(2'-Cyanobiphenyl-4-yl)amino]-5-ethylpyrazolo[1,5-a]pyrimidine | HCID 19975977 | — |
Reaction Steps
1.4 g (7.7 mmol) of the chloride from Example 1, Step B and 1.5 g (7.7 mmol) 4-Amino-2'-cyanobiphenyl were heated in 30 ml dry ethanol for 5 h. After removal of the solvent in vacuo the nitrile was obtained in colorless crystals from ethanol, m.p. 247°-248° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05571813 |
| Source dataset | uspto-grants-1996_11 |
| ORD ID | ord-f3564e07506243e8b16f4a76cfb69465 |
| Source note | uspto-grants-1996_11 |