p-Toluenesulfonic acid monohydrate → HCID 54488963, compound

Participants

Reaction Steps

A mixture of 2.84 g (7 mmol) of the same compound II as in Example 70, 1.05 g of p-toluenesulfonic acid monohydrate and 5 ml of glacial acetic acid was stirred at 70° for 2 hours and then worked up as. in Example 5. 2.03 g (=71.5% yield) of pure 4-amino-2-(4-vinyl-2-oxo-1-imidazolidinyl)pyrimidine-5-carboxylic acid N-methyl-N-(3-trifluoromethylphenyl)amide were obtained, melting point 203°-204°.

Provenance & Evidence