Oxalic Acid → HCID 54554829, compound

Participants

Reaction Steps

A mixture of 2.41 g (5 mmol) of a compound II (R1 =CH3 ; R2, R3, R5 =H; R4 =CH3CHCH2CH(CH3)2 ; R6 =F), 270 mg (3 mmol) of oxalic acid and 4.2 ml of propionic acid was stirred at 70° for 2 hours and then worked up as in Example 5. 1.50 g (62.3% yield) of the compound I (R1 =CH3 ; R2, R3, R5 =H ; R4 =CH3CHCH2CH(CH3)2 ; R6 =F) were obtained, melting point 135°-137°.

Provenance & Evidence