HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Amidino-4,4-diethyl-2-oxoimidazolidine hydrobromide → HCID 178428592, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Amidino-4,4-diethyl-2-oxoimidazolidine hydrobromide | HCID 23372861 | — |
| Reactant | 3-(Cycloundecen-1-yl)-1,2-diazacycloundec-2-ene | HCID 53630274 | — |
| Reactant | 2-cyano-3-ethoxyacrylic acid N-cyclopropylmethyl-N-(3-trifluoromethylphenyl)amide | HCID 54341639 | — |
| Product | HCID 178428592 | HCID 178428592 | 36.4% |
Reaction Steps
Starting from 6.58 g (24.8 mmol) of 1-amidino-4,4-diethyl-2-oxoimidazolidine hydrobromide (comp. III: R1, R2 =C2H5 ; R3 =H as hydrobromide) and 3.87 g (26.1 mmol) of diazabicycloundecene (DBU) as auxiliary base and 7.40 g (24.8 mmol) of a compound IV (R4 =CH3 ; R5, R6 =H; R7 =C3H5) by the procedure described in Examples 82-84, 3.94 g (=36.4% yield) of pure 1-cyano-1-[N-methyl-N-(3-trifluoromethylphenyl)carbamoyl]-2-[imino(4,4-diethyl-2-oxo-1-imidazolidinyl)methylamino]ethene (comp. II: R1, R2 =C2H5 ; R3, R5, R6 =H; R4 =CH3) were obtained, melting point 184°-87°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05571816 |
| Source dataset | uspto-grants-1996_11 |
| ORD ID | ord-e95aba98f6db42b4a8c21f14665131ff |
| Source note | uspto-grants-1996_11 |