Methyl iodide → HCID 86747977, compound

HRID 1898962Notes

Reaction equation

HRID 1898962 reaction equation
[CH3:1][I:2].[F:3][C:4]([F:23])([F:22])[CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][O:10][C:11]1[C:15]([C:16]2[CH:17]=[N:18][CH:19]=[CH:20][CH:21]=2)=[N:14][S:13][N:12]=1>CC(C)=O>[I-:2].[F:23][C:4]([F:3])([F:22])[CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][O:10][C:11]1[C:15]([C:16]2[CH:17]=[N+:18]([CH3:1])[CH:19]=[CH:20][CH:21]=2)=[N:14][S:13][N:12]=1

Participants

4

Reactant 2

HCID 6328Methyl iodideHCID 19612579HCID 19612579, compound

Product 1

HCID 86747977HCID 86747977, compound

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent

Procedure

A solution of methyl iodide (8.52 mg, 6.0 mmol) and 3-(3-(6,6,6-trifluorohexyloxy-1,2,5-thiadiazol-4-yl)pyridine (630 mg, 2.0 mmol) in acetone (25 ml) was refluxed for 7 h. The solution was evaporated and the residue was used directly in the next step.

Workup

  1. customThe solution was evaporated

Sources & evidence

ORD record
ord-cd42721deae24716a05d5434eba6fc44
Source dataset
uspto-grants-1996_11
Patent number
US05571826

Reaction notes

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