HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-[2-(Phenylmethoxy)ethyl]-N2-[[4-(phenylmethoxy)phenyl]methyl]glycinamide → N-[(Phenylmethoxy)carbonyl]-L-histidyl-N2-[4-(phenylmethoxy)butyl]-N-[2-(phenylmethoxy)ethyl]glycinamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-[2-(Phenylmethoxy)ethyl]-N2-[[4-(phenylmethoxy)phenyl]methyl]glycinamide | HCID 70182186 | — |
| Reactant | HCID 178523877 | HCID 178523877 | — |
| Reactant | Z-D-His-OH | HCID 178523878 | — |
| Product | N-[(Phenylmethoxy)carbonyl]-L-histidyl-N2-[4-(phenylmethoxy)butyl]-N-[2-(phenylmethoxy)ethyl]glycinamide | HCID 178521320 | — |
Reaction Steps
According to Example 10, Step 4, by substituting the compound from Step 1 above for N-[2-(phenylmethoxy)ethyl]-N2 -[[4-(phenylmethoxy)phenyl]methyl]glycinamide and CBZ-histidine for CBZ-D-histidine, the title compound was obtained as a white foam; ES-MS 642 (m+1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05571792 |
| Source dataset | uspto-grants-1996_11 |
| ORD ID | ord-eb0ed910c1a84304ae83fb373342fba5 |
| Source note | uspto-grants-1996_11 |