HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl iodide → HCID 23373068, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl iodide | HCID 6328 | — |
| Reactant | Potassium Cyanide | HCID 9032 | — |
| Reactant | 3-Dimethylaminomethyl-4-chloro-5-n-propyloxyindole | HCID 23373110 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 23373068 | HCID 23373068 | — |
Reaction Steps
Reaction of 3-dimethylaminomethyl-4-chloro-5-n-propyloxyindole (3.50 g, 13.1 mmol) with potassium cyanide (3.28 g, 50.4 mmol) and methyl iodide (7.44 g, 52.4 mmol) in DMF by the method described in 1 (d) gave 3-cyanomethyl-4-chloro-5-n-propyloxyindole as an oil which crystallised on standing (2.53 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05571833 |
| Source dataset | uspto-grants-1996_11 |
| ORD ID | ord-0a0bd58d125940f1996948fd04ff44e3 |
| Source note | uspto-grants-1996_11 |