Sulfuric Acid → 5-hydroxy-2,3-dihydro-1H-indene-1,3-dione

HRID 1899011Notes

Reaction equation

HRID 1899011 reaction equation
S(=O)(=O)(O)O.C([O:9][C:10]1[CH:11]=[C:12]2[C:16](=[CH:17][CH:18]=1)[C:15](=[O:19])[CH:14](C(OCC)=O)[CH:13]2[OH:25])(=O)C>O>[OH:9][C:10]1[CH:11]=[C:12]2[C:16](=[CH:17][CH:18]=1)[C:15](=[O:19])[CH2:14][C:13]2=[O:25]

Participants

4

Reactant 2

HCID 1118Sulfuric AcidHCID 190342875-Acetoxy-2-carbethoxy-3-hydroxy-1-indanone

Product 1

HCID 190343335-hydroxy-2,3-dihydro-1H-indene-1,3-dione

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

4 ml of 10N sulphuric acid were added to a suspension of 0.01 mol of 5-acetoxy-2-carbethoxy-3-hydroxy-1-indanone in 80 ml water. The reaction mixture was refluxed for 15 minutes. The insoluble substance was filtered when hot and the yellow precipitate formed after cooling was dried on vacuo pump, washed in ice water and dried.

Workup

  1. temperatureThe reaction mixture was refluxed for 15 minutes
  2. filtrationThe insoluble substance was filtered when hot
  3. customthe yellow precipitate formed
  4. temperatureafter cooling
  5. customwas dried on vacuo pump
  6. washwashed in ice water
  7. customdried

Sources & evidence

ORD record
ord-359fb786a915478ab624cf97e1ad2d7d
Source dataset
uspto-grants-1996_11
Patent number
US05571843

Reaction notes

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