Benzenesulfonyl chloride → HCID 15453203, compound

HRID 1899636Notes

Reaction equation

HRID 1899636 reaction equation
[C:1]1([S:7](Cl)(=[O:9])=[O:8])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[NH2:11][C:12]1[O:16][N:15]=[C:14]([C:17]2[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=2)[C:13]=1[Br:23]>>[Br:23][C:13]1[C:14]([C:17]2[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=2)=[N:15][O:16][C:12]=1[NH:11][S:7]([C:1]1[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1)(=[O:9])=[O:8]

Participants

3

Reactant 2

HCID 7369Benzenesulfonyl chlorideHCID 5829115-Amino-4-bromo-3-phenylisoxazole

Product 1

HCID 15453203HCID 15453203, compoundYield 36%

Procedure

This compound was prepared from benzenesulfonyl chloride and 5-amino-4-bromo-3-phenylisoxazole according to the method in Example 40b in 36% yield. Recrystallization from methanol gave a yellow solid, m.p. 113°-115° C.

Workup

  1. customRecrystallization from methanol
  2. customgave a yellow solid, m.p. 113°-115° C.

Sources & evidence

ORD record
ord-e32aff98ac4a44fdacab027f8878ffd5
Source dataset
uspto-grants-1996_11
Patent number
US05571821

Reaction notes

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