HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,3,4-Trichlorobenzenesulfonyl chloride → 2,3,4-Trichloro-N-(4-bromo-3-methyl-5-isoxazolyl)benzenesulfonamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,3,4-Trichlorobenzenesulfonyl chloride | HCID 36904 | — |
| Reactant | 4-Bromo-3-methylisoxazol-5-amine | HCID 10487519 | — |
| Product | 2,3,4-Trichloro-N-(4-bromo-3-methyl-5-isoxazolyl)benzenesulfonamide | HCID 18617341 | 66% |
Reaction Steps
2,3,4-Trichloro-N-(4-bromo-3-methyl-5-isoxazolyl)benzenesulfonamide was prepared from 5-amino-4-bromo-3-methylisoxazole and 2,3,4-trichlorobenzenesulfonyl chloride according to the procedures described in Example 45. The crude product was purified by recrystallization from ethyl acetate/hexanes to give a crystalline solid, m.p. 110°-113° C., yield 66%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05571821 |
| Source dataset | uspto-grants-1996_11 |
| ORD ID | ord-ecf8d502ae2e4322860f47d5b0079ff8 |
| Source note | uspto-grants-1996_11 |