Dimethylformamide → HCID 12218100, compound

Participants

Reaction Conditions

Reaction Steps

1,1-Diphenylethene (11.3 mmol, 2 ml) was added to a solution of DMF (22.7 mmol, 1.75 ml) and sulfuryl chloride (19.3 mmol, 1.55 ml) at 0° C. The reaction was heated to 90° C. for 4 hr, then cooled to ambient temperature and poured into ice (500 ml). The aqueous layer was extracted with EtOAc (2×100 ml). Then the organic was dried (MgSO4) filtered and concentrated. Flash chromatography (5% EtOAc/hexane) provided 0.92 g (29% yield) of light yellow crystals.

Provenance & Evidence