1,3-Dipropyl-8-cyclopentylxanthine → N6-2-(4-Aminophenyl)ethyladenosine

HRID 1899752Notes

Reaction equation

HRID 1899752 reaction equation
[C@@H:1]1([N:10]2[C:19]3[N:18]=[CH:17][N:16]=[C:14]([NH2:15])[C:13]=3[N:12]=[CH:11]2)[O:9][C@H:6]([CH2:7][OH:8])[C@@H:4]([OH:5])[C@H:2]1[OH:3].S([C:24]1C=CC(C2NC3C(=O)N(C)C(=O)N(C)C=3N=2)=C[CH:25]=1)(O)(=O)=O.[CH:43]1([C:48]2[NH:56]C3C(=O)N(CCC)C(=O)N(CCC)C=3N=2)[CH2:47][CH2:46][CH2:45][CH2:44]1>>[NH2:56][C:48]1[CH:43]=[CH:47][C:46]([CH2:45][CH2:44][NH:15][C:14]2[C:13]3[N:12]=[CH:11][N:10]([C:19]=3[N:18]=[CH:17][N:16]=2)[C@@H:1]2[O:9][C@H:6]([CH2:7][OH:8])[C@@H:4]([OH:5])[C@H:2]2[OH:3])=[CH:25][CH:24]=1

Participants

4

Reactant 3

HCID 13291,3-Dipropyl-8-cyclopentylxanthineHCID 19088-(4-Sulfophenyl)theophyllineHCID 60961Adenosine

Product 1

HCID 9952135N6-2-(4-Aminophenyl)ethyladenosine

Procedure

Adenosine (ADO) was obtained from Sigma. 8-(p-Sulfophenyl)-theophylline (SPT) and 8-cyclopentyl-1,3-dipropylxanthine (DPCPX) were purchased from Research Biochemicals Inc., Natick, Mass. N6 -(2-(4-aminophenyl)ethyl) adenosine (APNEA) was provided by Dr. Ray A. Olsson, Department of Internal Medicine, the University of South Florida, Tampa, Fla.

Sources & evidence

ORD record
ord-8010d478d9ae4f088b5e1923c78e1379
Source dataset
uspto-grants-1996_11
Patent number
US05573772

Reaction notes

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