HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triphenylphosphine → (E)-2-(1-methoxy-2-methoxycarbonylethenyl)benzyltriphenylphosphonium bromide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triphenylphosphine | HCID 11776 | — |
| Reactant | methyl (E)-2-bromomethyl-beta-methoxycinnamate | HCID 11219857 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | (E)-2-(1-methoxy-2-methoxycarbonylethenyl)benzyltriphenylphosphonium bromide | HCID 23371326 | 82.7% |
Reaction Steps
115 g (0.4 mol) of methyl (E)-2-bromomethyl-β-methoxycinnamate and 105 g (0.4 mol) of triphenylphosphine in 700 ml of tetrahydrofuran are refluxed for 24 h. Filtration with suction and washing with tetrahydrofuran result in 181 g (82% yield) of (E)-2-(1-methoxy-2-methoxycarbonylethenyl)benzyltriphenylphosphonium bromide in the form of colorless crystals with melting point 189-°192° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05573999 |
| Source dataset | uspto-grants-1996_11 |
| ORD ID | ord-80067e668ab04539b864004e5bf00d7b |
| Source note | uspto-grants-1996_11 |