173019-82-4 → 5-(Benzoxazol-2-ylsulfanyl)-5-[3-(4-chlorophenyl)-prop-2-ynyl]-thiazolidine-2,4-dione

HRID 1899887Notes

Reaction equation

HRID 1899887 reaction equation
[O:1]1[C:5]2[CH:6]=[CH:7][CH:8]=[CH:9][C:4]=2[N:3]=[C:2]1[S:10][CH:11]1[S:15][C:14](=[O:16])[NH:13][C:12]1=[O:17].[Cl:18][C:19]1[CH:24]=[CH:23][C:22]([C:25]#[C:26][CH2:27]Br)=[CH:21][CH:20]=1.FC1C=C(C#CCBr)C=C(F)C=1>>[O:1]1[C:5]2[CH:6]=[CH:7][CH:8]=[CH:9][C:4]=2[N:3]=[C:2]1[S:10][C:11]1([CH2:27][C:26]#[C:25][C:22]2[CH:23]=[CH:24][C:19]([Cl:18])=[CH:20][CH:21]=2)[S:15][C:14](=[O:16])[NH:13][C:12]1=[O:17]

Participants

4

Reactant 3

HCID 10513607173019-82-4HCID 199730395-(Benzoxazol-2-ylsulfanyl)-thiazolidine-2,4-dioneHCID 19973049HCID 19973049, compound

Product 1

HCID 199730515-(Benzoxazol-2-ylsulfanyl)-5-[3-(4-chlorophenyl)-prop-2-ynyl]-thiazolidine-2,4-dione

Procedure

Prepared from 5-(benzoxazol-2-ylsulfanyl)-thiazolidine-2,4-dione, (III), Example 89 and [3-(4-chlorophenyl)-prop-2-ynyl]-bromide of formula (IX), Example mp 137°-139° C.; Anal. Calc. for C19H11ClN2O3S2 : C, 55.80; H, 2.67; N, 6.75; Found: C, 54.92; H, 2.76; N, 6.82.

Sources & evidence

ORD record
ord-f4ae3802ce6d49fdae4280cdb5de7d38
Source dataset
uspto-grants-1996_11
Patent number
US05574051

Reaction notes

Loading…