6-Chloroimidazo[1,2-b]pyridazine-3-carbaldehyde → (6-Chloroimidazo[1,2-b]pyridazin-3-yl)(4,6-difluoro-1-methyl-1H-indazol-5-yl)methanol

HRID 190003Notes

Reaction equation

HRID 190003 reaction equation
[Cl:13][c:14]1[cH:15][cH:16][c:17]2[n:18]([c:19]([CH:20]=[O:21])[cH:22][n:23]2)[n:24]1.[Cl:25][c:26]1[cH:27][cH:28][c:29]2[n:30]([n:31]1)[c:32]([C:35]([CH3:36])([OH:37])[c:38]1[c:39]([F:49])[c:40]3[cH:41][n:42][n:43]([CH3:48])[c:44]3[cH:45][c:46]1[F:47])[cH:33][n:34]2.[F:1][c:2]1[cH:3][c:4]([F:5])[cH:6][c:7]2[c:8]1[cH:9][n:10][n:11]2[CH3:12]>>[Cl:25][c:26]1[cH:27][cH:28][c:29]2[n:30]([n:31]1)[c:32]([CH:35]([OH:37])[c:38]1[c:39]([F:49])[c:40]3[cH:41][n:42][n:43]([CH3:48])[c:44]3[cH:45][c:46]1[F:47])[cH:33][n:34]2

Participants

4

Reactant 3

HCID 114467026-Chloroimidazo[1,2-b]pyridazine-3-carbaldehydeHCID 579174794,6-Difluoro-1-methyl-1H-indazoleHCID 581475291-(6-Chloro-imidazo[1,2-b]pyridazin-3-yl)-1-(4,6-difluoro-1-methyl-1H-indazol-5-yl)-ethanol

Product 1

HCID 58190595(6-Chloroimidazo[1,2-b]pyridazin-3-yl)(4,6-difluoro-1-methyl-1H-indazol-5-yl)methanol

Sources & evidence

ORD record
ord-8e5034a6cef241ec9eaf4f9c475e2894
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

Loading…