Pyridine → HCID 54344752, compound

Participants

Reaction Steps

6.81 g (36.0 mmol) of 4-aminophenyl-cycloheptane were dissolved in 60 ml of methylene chloride and treated with 3.13 g (39.6 mmol) of pyridine. The reaction mixture was treated dropwise at room temperature while stirring with a solution of 4.3 g (39.6 mmol) of ethyl chloroformate in 15 ml of methylene chloride. After 2 hours the mixture was washed with water and the organic phase was dried over sodium sulfate, filtered and evaporated. The ethyl 4-cycloheptylphenyl-carbamate distilled at 165°-170° and 0.3 mbar.

Provenance & Evidence