HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → HCID 15380948, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Potassium Hydroxide | HCID 14797 | — |
| Reactant | Aluminium lithium hydride | HCID 21226445 | — |
| Reactant | 7-Benzyl-1-cyano-2-oxa-7-azabicyclo[3.3.0]octane | HCID 21704747 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 15380948 | HCID 15380948 | — |
Reaction Steps
10.2 g (40 mmol, 90% pure) of 7-benzyl-1-cyano-2-oxa-7-aza-bicyclo[3.3.0]octane are added dropwise to 2 g of lithium aluminium hydride in 100 ml of absolute tetrahydrofuran and the mixture is subsequently stirred under reflux for 15 hours. 2 ml each of water, 15% strength potassium hydroxide solution, and again water, are added dropwise, the inorganic salts are filtered off with suction, and the filtrate is concentrated and distilled.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05574161 |
| Source dataset | uspto-grants-1996_11 |
| ORD ID | ord-ef29ccd016e4441394435ce400651f8e |
| Source note | uspto-grants-1996_11 |