Water → 6-Chloropicolinic acid

HRID 1900606Notes

Reaction equation

HRID 1900606 reaction equation
[Cl:1][C:2]1[N:7]=[C:6]([CH3:8])[CH:5]=[CH:4][CH:3]=1.[O-:9][Mn](=O)(=O)=O.[K+].[OH2:15]>>[Cl:1][C:2]1[N:7]=[C:6]([C:8]([OH:9])=[O:15])[CH:5]=[CH:4][CH:3]=1

Participants

4

Reactant 3

HCID 962Water2×HCID 876016-Chloro-2-picolineHCID 516875Potassium Permanganate

Product 1

HCID 208126-Chloropicolinic acid

Conditions

Temperature
90 °C

Procedure

A mixture of 3.8 g (0.03 mol) of 6-chloro-2-methylpyridine and 10.45 g of KMnO4 in 380 ml of water is heated to 90° C. for 6 hours. The product is cooled, the pH is adjusted to approximately 4, water is evaporated off and the residue is taken up with ethanol. It is filtered and the ethanol is evaporated to produce 1.1 g of the compound referred to above.

Workup

  1. temperatureThe product is cooled
  2. customis evaporated off
  3. filtrationIt is filtered
  4. customthe ethanol is evaporated

Sources & evidence

ORD record
ord-d33adcfa2e7a448fbea651167248be5a
Source dataset
uspto-grants-1996_11
Patent number
US05576320

Reaction notes

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