HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ammonia → 4-(alpha-Carbamoyl-3,4-methylenedioxybenzyl)amino-6-chloroquinazoline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ammonia | HCID 222 | — |
| Reactant | HCID 18796707 | HCID 18796707 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 4-(alpha-Carbamoyl-3,4-methylenedioxybenzyl)amino-6-chloroquinazoline | HCID 18796704 | 32% |
Reaction Steps
20 ml of a 10% solution of ammonia in ethanol was added to 200 mg of 4-(α-ethoxycarbonyl-3,4-methylenedioxybenzyl)amino-6-chloroquinazoline. The obtained mixture was stirred at room temperature for 3 days. The crystal thus precipitated was recovered by filtration. Thus, 60 mg of the title compound was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05576322 |
| Source dataset | uspto-grants-1996_11 |
| ORD ID | ord-c03a811ea26b4c1aaf85f46e028ec4fc |
| Source note | uspto-grants-1996_11 |