Methylamine → HCID 178485035, compound

Participants

Reaction Conditions

Reaction Steps

The compound obtained in Example 212 (0.66 g, 2.01 mmol) was dissolved in a mixture of ethanol (30 ml) and dimethylformamide (50 ml). To the obtained solution, 30% methylamine in ethanol (25 ml) was added and stirred at 80° C. for 1.5 hours. The solvent was distilled off under reduced pressure, and the residue was washed with ethanol. 0.626 g (assayed quantitatively) of the title compound was obtained as a pale yellow solid. The solid was recrystallized from chloroform--methanol--ether, to obtain the title compound as colorless needles (mp. 262°-265° C. (dec.)).

Provenance & Evidence