Methanol → HCID 23369766, compound

Participants

Reaction Steps

The compound obtained in Example 233 (1.2 g, 3.5 mmol) was dissolved in water (40 ml). To the obtained solution, 10% palladium-on-carbon (1.3 g) was added, followed by stirring at 80° C. for 12 hours in the atmosphere of hydrogen. The reaction mixture was filtered, and the filtrate was condensed under reduced pressure. The resultant residue was subjected to a recrystallizing procedure using chloroform--methanol--ether to obtain 690 mg of the title compound as colorless powdery crystals (58.0%).

Provenance & Evidence