N-bromobutanimide → HCID 23369697, compound

Participants

Reaction Conditions

Reaction Steps

6-Allyl-5-hydroxy-3,4,8-trimethylcarbostyril (1.01 g, 4.16 mmol) was dissolved in chloroform (50 ml). To the obtained solution, N-bromosuccinimide (888 mg, 4.99 mmol) was added. The mixture was refluxed with in a bath of 100° C. for 1.5 hours. The reaction mixture was cooled, washed with saturated aqueous NaCl solution and dried. The solvent was distilled off under reduced pressure. The residue was recrystallized from chloroform--ether to obtain 1.06 g of the title compound as yellow needles (79.8%).

Provenance & Evidence