反应详情

温度

75 °C

To 6-allyl-5-hydroxy-3,8-dimethylcarbostyril (3.86 g, 16.68 mmol), N-bromsuccinimide (3.0 g, 16.68 mmol) and chloroform (140 ml) were added, and stirred for 25 minutes in a bath at 75° C. After cooling, the mixture was washed with water, dried, and condensed. The resultant residue was subjected to recrystallization (chloroform-methanol-ether) to obtain 3.36 g of the title compound as pale yellow prisms (64.7%).

1. temperatureAfter cooling
2. washthe mixture was washed with water
3. customdried
4. customcondensed
5. customThe resultant residue was subjected to recrystallization (chloroform-methanol-ether)