HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Chloro-2-methyl-1-propene → 5-(2-Methyl-2-propenyl)oxy-3,8-dimethylcarbostyril
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Chloro-2-methyl-1-propene | HCID 11241 | — |
| Reactant | 3,8-Dimethyl-5-hydroxycarbostyril | HCID 23369624 | — |
| Product | 5-(2-Methyl-2-propenyl)oxy-3,8-dimethylcarbostyril | HCID 23369812 | 90.1% |
Reaction Steps
Reaction, post-treatment, and recrystallization (chloroform-n-hexane) were performed in a manner similar to that described in Reference Example 31 using 5-hydroxy-3,8-dimethylcarbostyril (3 g, 15.87 mmol) and 3-chloro-2-methyl-1-propene (1.58 g, 17.46 mmol). As a result, 3.48 g of the title compound was obtained as pale brown crystals (90.2%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05576324 |
| Source dataset | uspto-grants-1996_11 |
| ORD ID | ord-f4ace0fed2954d6b93cd2238c94b6f09 |
| Source note | uspto-grants-1996_11 |