HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Butene, 1-bromo-3-methyl- → 5-(3-Methyl-2-butenyl)oxy-3,8-dimethylcarbostyril
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Butene, 1-bromo-3-methyl- | HCID 70092 | — |
| Reactant | 3,8-Dimethyl-5-hydroxycarbostyril | HCID 23369624 | — |
| Product | 5-(3-Methyl-2-butenyl)oxy-3,8-dimethylcarbostyril | HCID 23369815 | 73.9% |
Reaction Steps
Reaction, post-treatment, and recrystallization (chloroform-n-hexane) were performed in a manner similar to that described in Reference Example 31 using 5-hydroxy-3,8-dimethylcarbostyril (1.4 g, 7.41 mmol) and 4-bromo-2-methyl-2-butene (1.21 g, 8.15 mmol). As a result, 1.41 g of the title compound was obtained as colorless crystals (74.1%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05576324 |
| Source dataset | uspto-grants-1996_11 |
| ORD ID | ord-72fb254caebb4ecd8375b82adb7299b7 |
| Source note | uspto-grants-1996_11 |