Sodium Azide → HCID 23369791, compound

Participants

Reaction Conditions

Reaction Steps

To a mixture of 2-iodomethyl-2,3,5,8-tetramethyl-2,3,6,7-tetrahydrofuro[2,3-f]quinoline-7-one (1.75 g, 4.57 mmol) and sodium azide (3.5 g, 53.8 mmol), dimethylformamide (24 ml) was added, and the mixture was stirred for 3 hours in a bath at 150° C. After cooling, post-treatment and recrystallization (chloroform-n-hexane) were performed in a manner similar to that described in Example 278 to obtain 1.13 g of the title compound as pale yellow crystals (83.0%).

Provenance & Evidence